🇪🇸 100% SPAIN STOCK·FAST 24-72H DISPATCH

iberialabs
COMPOUND · SEM-041426102% FILL
semax 10 mg
Cognitive
EXP: 04/2028

semax

Rapidly increases BDNF and NGF neurotrophic factors, resulting in potent neuroprotection, enhanced focus, mental clarity, and cognitive regeneration.

LOT:SEM-041426
CALCULATOR↗LAB REPORT (COA)↗
OUT OF STOCK0 VIALS AVAILABLE IN STOCK
100% EU Delivery Guarantee— free reshipment if lost
24h EU dispatch from Spain · Zero customs risk
HPLC certified purity >99% on every batch
FOR LABORATORY USE ONLY — NOT FOR HUMAN CONSUMPTION. SHIPS FROM THE EU WITHIN 24 H, EU DELIVERY 3-7 DAYS, SPAIN 1-3 DAYS.

what the literature shows.

A condensed monograph drawn from preclinical and clinical literature, cited mechanisms, specifications and the research case for semax.

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Semax: The Modified Heptapeptide for Neuroprotection and Nootropic Induction

Semax is a synthetic peptide known in Russian neurology for its neuroprotective, nootropic, and neurotrophic properties.40

Structural Parameters of Semax

PropertyValue and SpecificationReferences
CAS Number80714-61-038
Molecular FormulaC37H51N9O10S38
Molecular Weight813.92 g/mol38
SequenceMet-Glu-His-Phe-Pro-Gly- Pro (ACTH4-7-PGP)40
Isoelectric Point~5.242

Origin, History, and Research Stage

Semax was developed in the 1980s by the Institute of Molecular Genetics of the Russian Academy of Sciences, led by researcher Igor Ashmarin . The design aimed to retain the cognitive benefits of adrenocorticotropic hormone (ACTH) fragments without inducing peripheral steroidal or adrenal side effects.44 Semax was registered with the Russian Ministry of Health in 1994 for ischemic stroke, traumatic brain injury, and cognitive disorders.44 In 2011 and 2019, it was included on the Russian List of Vital & Essential Drugs.45 In Western markets, it is not FDA-approved and remains classified as a research chemical, although it is prescribed through 503A compounding pharmacies for cognitive enhancement.44

Mechanism of Action and Pharmacokinetics

Semax is a synthetic heptapeptide derived from the ACTH4-7 fragment (Met-Glu-His-Phe), stabilized by a C-terminal tripeptide sequence (Pro-Gly-Pro or PGP).40 This addition protects the peptide from immediate degradation by blood peptidases, extending its half-life and enabling intranasal absorption.44 Semax binds to melanocortin receptors (primarily MC4R) and upregulates the expression of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) in the hippocampus and cortex.44 Animal models show a 1.4-fold increase in BDNF protein and enhanced phosphorylation of tyrosine kinase B (TrkB) receptors within 3 hours.44 During ischemic events, Semax downregulates the apoptotic marker pJNK and matrix metalloproteinase-9 (MMP-9), while upregulating the survival transcription factor pCREB, mitigating cell death in the ischemic penumbra.39 It also sequesters copper divalently to reduce amyloid-beta (Ab1-42) aggregation.47

Scientific and Clinical Effects

In clinical trials, intranasal Semax (6,000 mcg/day) improved motor recovery and daily living scores (Barthel Index) in patients recovering from acute ischemic stroke.44 Electrophysiological trials confirm that Semax induces changes in EEG mapping, indicating increased default mode network (DMN) connectivity.44 This connectivity supports memory consolidation, attention accuracy under stress, and sustained mental focus.44

Verified Reviews.

4.5 / 5.0
★★★★★
Based on 2 reviews
2 total reviews
★★★★★
🇵🇱Jul 29, 2026

Great focus for study sessions

Package arrived in Warsaw in 5 days. Quality is solid and clarity/focus during working hours is noticeably improved. Good pricing for EU shipping without customs hassle.

Purchased Items:

• 1x Semax 10mg
• 1x Selank 10mg
• 1x BAC Water 10ml
P
Piotr
Warszawa, Poland✓ Verified
★★★★★
🇪🇸Apr 29, 2026

Great for my Medicine final exams.

Exceptional service, top-notch peps. Also pretty cheap. 6 days to Fr.

Purchased Items:

• 1x Selank 10mg
• 1x Semax 10mg
• 1x BAC Water 10ml.
E
Emma Novak
Nantes, France✓ Verified
/ FREQUENTLY ASKED QUESTIONS & PROTOCOLS

Frequently asked questions about semax.

Technical reconstitution protocols, HPLC purity verification, storage conditions, and express European delivery details.

semax is brought into solution using the diluent specified on its technical datasheet: sterile bacteriostatic water or 0.9% NaCl. Insert the syringe and direct the stream gently against the inner vial wall. Swirl smoothly with circular motions rather than shaking vigorously, as mechanical agitation can shear delicate peptide chains. Once reconstituted, it remains stable refrigerated at 2–8 °C for up to 28 days.

At Iberia Labs, every batch of semax is verified by High-Performance Liquid Chromatography (HPLC) at ≥ 99.877% purity, with bacterial endotoxin levels strictly under 0.5 EU/mg and identity confirmed by Mass Spectrometry (MS). Each batch is backed by its lot-specific Certificate of Analysis (current lot: SEM-041426).

Lyophilized semax in vacuum-sealed vials should be stored at -20 °C, protected from light and moisture, with an unopened shelf life of 24 to 36 months. The sealed powder readily tolerates ambient temperature during transit without loss of potency. Upon receipt, transfer immediately to cold storage (-20 °C unopened, or 2–8 °C once reconstituted).

semax is available directly from Iberia Labs (iberialabs.eu), dispatched from warehouses within the European Union and Spain. Because shipments originate within the EU single market, orders are completely free from customs clearance delays. Orders dispatch within 24 hours, with 24–72 hour delivery in Spain and 2–5 business days across Europe.

Yes, semax may be legally purchased in Spain and throughout the European Union strictly for laboratory research, chemical analysis, and in-vitro or preclinical investigation (RUO). Iberia Labs supplies analytical-grade reagents exclusively to the scientific and research community. It is not an approved medicine and is not intended for human or animal consumption, nor for clinical diagnostics.

semax is available in individual vials (10 mg) starting at €35.95. Every order includes its verified lot-specific Certificate of Analysis at no extra cost. Prices are quoted in EUR and express shipping options are transparently calculated at checkout.

All confirmed orders of semax are dispatched within 24 business hours from our EU fulfillment facilities. Delivery across mainland Spain takes 24–72 hours via express courier. International European destinations arrive within 2–4 business days with secure and discreet packaging.

Yes. Every vial of semax is accompanied by an authentic Certificate of Analysis (CoA) for the current batch (SEM-041426). The report documents HPLC purity chromatograms, mass spectrometry identity validation, and endotoxin assays. You can view and download the full laboratory report directly in our Lab Report (CoA) section.