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QUALITY ASSURANCE·
2026-09-18
·
5 min

How to Read a Peptide Certificate of Analysis (CoA): HPLC & MS Verification

Analytical criteria to assess genuine purity and detect fraudulent certificates in research reagents.

Dpto. Calidad Analítica IberiaLabs

How to Interpret Peptide Analytical Certificates

A genuine Certificate of Analysis (CoA) provides two distinct confirmations:

  1. Purity (HPLC): Demonstrates that >99% of detected molecules belong to the primary peak.
  2. Identity (LC-MS): Verifies exact molecular weight against theoretical sequence specifications.

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